000			02097 a2200205 4500
008			160114b xxu||||| |||| 00| 0 eng d
020			_a978-81-224-0943-7
082			_a615
100			_aPandeya, S N _920375
245			_aAn Introduction to Drug Design _cD. J. Rimmock and S N Pandeya,
260			_bNew age International (P) Limited Publisher _aNew Delhi _c1997
300			_a214 p. _bPaper
505			_aSection I Development of New Drugs Section II Prodrugs and Soft Drugs Section III Chemical Parameters in Drug Design Section IV Physicochemical Parameters in Drug Design Section V Design of Enzyme Inhibitors Section VI Drug Metabolism Section VII Molecular Modelling Using Computers Section VIII Structure-Based Drug Design.
520			_aThe book entitled, An Introduction to Drug Design aims to optimize the discovery of drugs at a low cost and on occasions to change their pharmacokinetic and pharmacodyanamic properties. The introductory chapter which forms the basis of drug discovery is followed by the present-day thinking regarding the best approaches to drug discovery are considered. Similarly, there have been major advances in the employment of computers in structure-activity analysis, and a discussion of the state of the art in this area is also included. The chapter on QSAR highlights the role of physico-chemical parameters in predicting the future course of drug discovery with rational drug design. The role of enzymes in drug action is well established, and a chapter on design of enzyme inhibitors is well documented. In addition, the increased understanding of the design and utilisation of prodrugs has led to a discussion of the relevant issues in this text. Thus the book will fill the need of a text for designing new drugs and the principles of new drug discovery.
650			_aPharmaceutical management _920376
650			_aDrug Design _920377
700			_aDimmock, J R _920378
942			_2ddc _cBK
999			_c41020 _d41020